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Distinctive Value 

The certified reference material (CRM) for drinking water contains 29 elements with certified concentrations, including those regulated by the European Directive 2020/2184. ISC-Science’s reference materials are produced and certified under ISO 17034 and accredited by the National Accreditation Body (ENAC). Using high-precision Inductively Coupled Plasma Mass Spectrometry (ICP-MS), these materials guarantee accuracy and precision in detecting elements in drinking water.

Key Benefits

  • Method Validation and Verification: These CRMs are ideal for validating and verifying analytical methods, used in the determination of elements in drinking water.
  • Trueness, Accuracy and Precision Quality Control: Laboratories can effectively monitor and enhance the accuracy, bias, and precision using these CRMs.
  • High Stability: Stability of these materials are based upon rigorous long-term (storage conditions) and short-term (transport conditions) testing for the certified values according to ISO 17034, ISO 17025 and ISO Guide 35.
  • Uncertainty and Traceability: The certified concentration values are traceable to primary standards from NIST and SI to ensure the highest accuracy, low uncertainty and complete traceability.
  • Versatility: These materials are suitable for homogeneity and stability studies and can be applied across a wide range of chemical analysis methodologies.

CRM of Drinking Water Features:

  • Composition: Solutions containing elements in drinking water, stabilized using ultra-pure acid, to ensure long-term stability.
  • Certified Concentrations: The element concentration is quantified using high-precision methodologies, expressed in milligrams per liter (mg/L) or micrograms per liter (µg/L).
  • Uncertainty budget: The expanded uncertainty of certified values is calculated following ISO Guide 35, where k = 2 is the coverage factor for a 95% confidence interval, ensuring full reliability and traceability.
  • Packaging: The material is provided in low-density polyethylene (LDPE) bottles, designed to maintain the integrity of the contents throughout storage and usage. This CRM is stable at room temperature and can be used directly or with an appropriate dilution.
  • Certification Process: Certified under ISO 17034, the material passed through rigorous homogeneity and stability studies, to guarantee consistent performance in analytical applications.
Reference Materials for Laboratories: Precision and Quality Guaranteed.


A reference material is essential for laboratories that prioritize precision and reliability. It is a substance with homogeneous and stable properties, making it ideal for instrument calibration, method verification, and ensuring the quality of results. These materials play a critical role in validating methods, estimating uncertainties, and ensuring the traceability of obtained data.

Certified Reference Materials (CRMs): Your Quality Control Ally.


Implementing an effective quality control system in a laboratory requires robust tools like Certified Reference Materials (CRMs). These materials ensure the accuracy and traceability of results in both calibrations and testing, complying with the highest international standards, such as those outlined in ISO Guide 33.

ISC-Science: Over 20 Years Leading the Production of Certified Reference Materials.


With nearly two decades of experience, ISC-Science is a leading manufacturer of isotopic standards and CRMs, accredited by Spanish Accreditataion Body (ENAC-accreditation no. 3/PMR004). ISC-Science has expanded its product range to include certified reference materials for determining elemental content in clean water, adhering to the stringent ISO 17034 standard.

Commitment to Quality and Stability.


The stability of our materials is guaranteed through rigorous long-term stability studies and transportation condition assessments, following ISO Guide 35 guidelines. Quality is non-negotiable, which is why ISC-Science is dedicated to offering materials that maintain their integrity and precision, even under the most demanding conditions.

Ensure the Quality of Your Results with ISC-Science Certified Reference Materials!

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